Jurgen Klopp's Reds accumulated 99 points, one fewer than Manchester City managed two years ago, and one more than Liverpool managed in 1978-79, once the two points they got for a win back then is altered to three.
They finished 18 points above Pep Guardiola's runners-up - one short of City's record winning margin two seasons ago.
Dwight Gayle put Newcastle ahead after 25 seconds from Jonjo Shelvey's free-kick, the fastest goal ever scored on a Premier League final day.
But Liverpool, who left their vaunted front three of Mohamed Salah, Sadio Mane and Roberto Firmino on the bench, levelled through Virgil van Dijk's header.
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